Antidepressant risk in bipolar sufferers limited to monotherapy use By Eleanor McDermid.

Antidepressant risk in bipolar sufferers limited to monotherapy use By Eleanor McDermid, Senior medwireNews Reporter Antidepressants may cause problems in sufferers with bipolar disorder only when they are used in isolation, research suggests. The results, published in The American Journal of Psychiatry, indicate that antidepressants do not significantly increase the risk of mania if they are used in conjunction with a mood stabiliser. The group used Swedish nationwide registry data to identify sufferers with bipolar disorder who began antidepressant therapy carrying out a year free from antidepressant treatment apotek .

Reducing bleeding occasions in sufferers receiving antithrombotic therapy is definitely important since bleeding events are associated with improved mortality. Fondaparinux was associated with reduced main bleeding events and improved survival weighed against LMWH in a big randomized clinical trial involving patients with non-ST-segment elevation myocardial infarction . Large-scale connection with the usage of fondaparinux vs LMWH outside of a medical trial setting provides been lacking, according to background information in the article. Karolina Szummer, M.D., Ph.D., of the Karolinska Institutet, Stockholm, Sweden, and colleagues analyzed data from a Swedish registry that included 40,616 individuals with NSTEMI who received in-medical center treatment with fondaparinux or LMWH between September 2006 through June 2010, through December 2010 with follow-up.