Malignancy survivors in rural areas much more likely to forgo health care because of financial concerns Older cancer survivors living in rural areas were much more likely to forgo medical and dental care due to financial concerns compared with older cancer survivors surviving in urban areas, according to a study published in Cancer Epidemiology, Biomarkers & Avoidance, a journal of the American Association for Malignancy Research. Data analysis showed malignancy survivors in rural areas who were aged 65 or older were 66 % much more likely to forgo medical care and 54 % more likely to forgo dental hygiene because of cost, compared with their urban counterparts. ‘This is actually the first population-based study to examine whether cancers survivors in rural and cities are equally more likely to forgo health care because of concerns about price,’ stated Nynikka Palmer, Dr.P.H., M.P.H., postdoctoral fellow in the Section of Social Health and Sciences Plan at Wake Forest College of Medicine in Winston-Salem, N.C.Amlexanox seems to function in mice by inhibiting two genes-IKKE and TBK1-that we think together act as sort of brake on metabolism, Saltiel stated. By releasing the brake, amlexanox appears to free the metabolic system to burn more, and store less possibly, energy. Using high-throughput chemical screening at LSI's Center for Chemical substance Genomics to find substances that inhibit IKKE and TBK1, the researchers strike upon an approved off-patent drug: amlexanox.